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Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues
Transient receptor potential melastatin‐2 (TRPM2) channel critical for monitoring internal body temperature is implicated in the pathological processes such as neurodegeneration. However, lacking selective and potent TRPM2 inhibitors impedes investigation and validation of the channel as a drug targ...
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| Publicado no: | Chem Biol Drug Des |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5813235/ https://ncbi.nlm.nih.gov/pubmed/29034580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13119 |
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