Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2

Activation of the transient receptor potential melastatin 2 (TRPM2) channel occurs during the response to oxidative stress under physiological conditions as well as in pathological processes such as ischemia and diabetes. Accumulating evidence indicates that adenosine diphosphate ribose (ADPR) is th...

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Gepubliceerd in:J Gen Physiol
Hoofdauteurs: Yu, Peilin, Xue, Xiwen, Zhang, Jianmin, Hu, Xupang, Wu, Yan, Jiang, Lin-Hua, Jin, Hongwei, Luo, Jianhong, Zhang, Liangren, Liu, Zhenming, Yang, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299621/
https://ncbi.nlm.nih.gov/pubmed/28108595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611675
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