Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2

Activation of the transient receptor potential melastatin 2 (TRPM2) channel occurs during the response to oxidative stress under physiological conditions as well as in pathological processes such as ischemia and diabetes. Accumulating evidence indicates that adenosine diphosphate ribose (ADPR) is th...

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Опубликовано в: :J Gen Physiol
Главные авторы: Yu, Peilin, Xue, Xiwen, Zhang, Jianmin, Hu, Xupang, Wu, Yan, Jiang, Lin-Hua, Jin, Hongwei, Luo, Jianhong, Zhang, Liangren, Liu, Zhenming, Yang, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2017
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299621/
https://ncbi.nlm.nih.gov/pubmed/28108595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611675
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