Progesterone Receptor Membrane Component 1 suppresses the p53 and Wnt/β-catenin pathways to promote human pluripotent stem cell self-renewal

Progesterone receptor membrane component 1 (PGRMC1) is a multifunctional heme-binding protein involved in various diseases, including cancers and Alzheimer’s disease. Previously, we generated two monoclonal antibodies (MAbs) 108-B6 and 4A68 against surface molecules on human pluripotent stem cells (...

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Publicat a:Sci Rep
Autors principals: Kim, Ji Yea, Kim, So Young, Choi, Hong Seo, Kim, Min Kyu, Lee, Hyun Min, Jang, Young-Joo, Ryu, Chun Jeih
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813096/
https://ncbi.nlm.nih.gov/pubmed/29445107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21322-z
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