Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cells

Abstract Background The differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts (OBs) is a prerequisite for bone formation. However, little is known about the definitive surface markers for OBs during osteogenesis. Methods To study the surface markers on OBs, we generated and used m...

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Main Authors: Hyun Min Lee, Se-Ri Seo, Jeeseung Kim, Min Kyu Kim, Hyosun Seo, Kyoung Soo Kim, Young-Joo Jang, Chun Jeih Ryu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-06-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Human mesenchymal stem cells
Osteoblasts
Monoclonal antibodies
Osteogenic differentiation
Integrin αV
Integrin α3
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01714-7
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