A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics

Despite the success of large-scale genome-wide association studies (GWASs) on complex traits, our understanding of their genetic architecture is far from complete. Jointly modeling multiple traits’ genetic profiles has provided insights into the shared genetic basis of many complex traits. However,...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Lu, Qiongshi, Li, Boyang, Ou, Derek, Erlendsdottir, Margret, Powles, Ryan L., Jiang, Tony, Hu, Yiming, Chang, David, Jin, Chentian, Dai, Wei, He, Qidu, Liu, Zefeng, Mukherjee, Shubhabrata, Crane, Paul K., Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812911/
https://ncbi.nlm.nih.gov/pubmed/29220677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.11.001
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