A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics

Despite the success of large-scale genome-wide association studies (GWASs) on complex traits, our understanding of their genetic architecture is far from complete. Jointly modeling multiple traits’ genetic profiles has provided insights into the shared genetic basis of many complex traits. However,...

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Publicado en:Am J Hum Genet
Autores principales: Lu, Qiongshi, Li, Boyang, Ou, Derek, Erlendsdottir, Margret, Powles, Ryan L., Jiang, Tony, Hu, Yiming, Chang, David, Jin, Chentian, Dai, Wei, He, Qidu, Liu, Zefeng, Mukherjee, Shubhabrata, Crane, Paul K., Zhao, Hongyu
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812911/
https://ncbi.nlm.nih.gov/pubmed/29220677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.11.001
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