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Adjustment for Covariates Using Summary Statistics in GWAS analysis

Linear regression is a standard approach to identify genetic variants associated with continuous traits in genome-wide association studies (GWAS). In a standard epidemiology study, linear regression is often performed with adjustment for covariates to estimate the independent effect of a predictor v...

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Bibliographische Detailangaben
Veröffentlicht in:Genet Epidemiol
Hauptverfasser: Wang, Tao, Xue, Xiaonan, Xie, Xianhong, Ye, Kenny, Zhu, Xiaofeng, Elston, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239891/
https://ncbi.nlm.nih.gov/pubmed/30238496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22148
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