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Multiscale Kinetic Modeling Reveals an Ensemble of Cl(–)/H(+) Exchange Pathways in ClC-ec1 Antiporter
[Image: see text] Despite several years of research, the ion exchange mechanisms in chloride/proton antiporters and many other coupled transporters are not yet understood at the molecular level. Here, we present a novel approach to kinetic modeling and apply it to ion exchange in ClC-ec1. Our multis...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2018
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812667/ https://ncbi.nlm.nih.gov/pubmed/29332400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11463 |
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