Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression

BACKGROUND: Non-invasive monitoring of epidermal growth factor receptor (EGFR) mutations conferring sensitivity and resistance to tyrosine kinase inhibitors (TKIs) is vital for efficient therapy of lung adenocarcinoma (LADC). Although plasma circulating cell-free tumour DNA (ctDNA) is detectable at...

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Bibliografski detalji
Izdano u:ESMO Open
Glavni autori: Seki, Yoshitaka, Fujiwara, Yutaka, Kohno, Takashi, Yoshida, Kazushi, Goto, Yasushi, Horinouchi, Hidehito, Kanda, Shintaro, Nokihara, Hiroshi, Yamamoto, Noboru, Kuwano, Kazuyoshi, Ohe, Yuichiro
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2018
Teme:
Translational Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://ncbi.nlm.nih.gov/pubmed/29464111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000292
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