Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression

BACKGROUND: Non-invasive monitoring of epidermal growth factor receptor (EGFR) mutations conferring sensitivity and resistance to tyrosine kinase inhibitors (TKIs) is vital for efficient therapy of lung adenocarcinoma (LADC). Although plasma circulating cell-free tumour DNA (ctDNA) is detectable at...

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發表在:ESMO Open
Main Authors: Seki, Yoshitaka, Fujiwara, Yutaka, Kohno, Takashi, Yoshida, Kazushi, Goto, Yasushi, Horinouchi, Hidehito, Kanda, Shintaro, Nokihara, Hiroshi, Yamamoto, Noboru, Kuwano, Kazuyoshi, Ohe, Yuichiro
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2018
主題:
Translational Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://ncbi.nlm.nih.gov/pubmed/29464111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000292
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