Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression

BACKGROUND: Non-invasive monitoring of epidermal growth factor receptor (EGFR) mutations conferring sensitivity and resistance to tyrosine kinase inhibitors (TKIs) is vital for efficient therapy of lung adenocarcinoma (LADC). Although plasma circulating cell-free tumour DNA (ctDNA) is detectable at...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Seki, Yoshitaka, Fujiwara, Yutaka, Kohno, Takashi, Yoshida, Kazushi, Goto, Yasushi, Horinouchi, Hidehito, Kanda, Shintaro, Nokihara, Hiroshi, Yamamoto, Noboru, Kuwano, Kazuyoshi, Ohe, Yuichiro
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://ncbi.nlm.nih.gov/pubmed/29464111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000292
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