Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression

BACKGROUND: Non-invasive monitoring of epidermal growth factor receptor (EGFR) mutations conferring sensitivity and resistance to tyrosine kinase inhibitors (TKIs) is vital for efficient therapy of lung adenocarcinoma (LADC). Although plasma circulating cell-free tumour DNA (ctDNA) is detectable at...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:ESMO Open
Autori principali: Seki, Yoshitaka, Fujiwara, Yutaka, Kohno, Takashi, Yoshida, Kazushi, Goto, Yasushi, Horinouchi, Hidehito, Kanda, Shintaro, Nokihara, Hiroshi, Yamamoto, Noboru, Kuwano, Kazuyoshi, Ohe, Yuichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2018
Soggetti:
Translational Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812398/
https://ncbi.nlm.nih.gov/pubmed/29464111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000292
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi