Membrane depolarization activates BK channels through ROCK-mediated β1 subunit surface trafficking to limit vasoconstriction

Membrane depolarization of smooth muscle cells (myocytes) in the small arteries that regulate regional organ blood flow leads to vasoconstriction. Membrane depolarization also activates large-conductance calcium (Ca(2+))–activated potassium (BK) channels, which limits Ca(2+) channel activity that pr...

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Detaylı Bibliyografya
Yayımlandı:Sci Signal
Asıl Yazarlar: Leo, M. Dennis, Zhai, Xue, Muralidharan, Padmapriya, Kuruvilla, Korah P., Bulley, Simon, Boop, Frederick A., Jaggar, Jonathan H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812274/
https://ncbi.nlm.nih.gov/pubmed/28487419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aah5417
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