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Membrane depolarization activates BK channels through ROCK-mediated β1 subunit surface trafficking to limit vasoconstriction
Membrane depolarization of smooth muscle cells (myocytes) in the small arteries that regulate regional organ blood flow leads to vasoconstriction. Membrane depolarization also activates large-conductance calcium (Ca(2+))–activated potassium (BK) channels, which limits Ca(2+) channel activity that pr...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812274/ https://ncbi.nlm.nih.gov/pubmed/28487419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aah5417 |
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