Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction

Arterial smooth muscle cells (myocytes) express large-conductance Ca(2+)-activated K(+) (BK) channel α and auxiliary β1 subunits that modulate arterial contractility. In arterial myocytes, β1 subunits are stored within highly mobile rab11A-positive recycling endosomes. In contrast, BKα subunits are...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Leo, M. Dennis, Bulley, Simon, Bannister, John P., Kuruvilla, Korah P., Narayanan, Damodaran, Jaggar, Jonathan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572372/
https://ncbi.nlm.nih.gov/pubmed/26179602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00127.2015
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