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Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice
BACKGROUND: Trovafloxacin is a broad-spectrum antibiotic, recently identified as an inhibitor of pannexin-1 (Panx1) channels. Panx1 channels are important conduits for the adenosine triphosphate (ATP) release from live and dying cells that enhances the inflammatory response of immune cells. Elevated...
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| Pubblicato in: | J Neuroinflammation |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812039/ https://ncbi.nlm.nih.gov/pubmed/29439712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1069-9 |
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