Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice

BACKGROUND: Trovafloxacin is a broad-spectrum antibiotic, recently identified as an inhibitor of pannexin-1 (Panx1) channels. Panx1 channels are important conduits for the adenosine triphosphate (ATP) release from live and dying cells that enhances the inflammatory response of immune cells. Elevated...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Garg, Charu, Seo, Joon Ho, Ramachandran, Jayalakshmi, Loh, Ji Meng, Calderon, Frances, Contreras, Jorge E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812039/
https://ncbi.nlm.nih.gov/pubmed/29439712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1069-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker