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MEK inhibitor trametinib attenuates neuroinflammation and cognitive deficits following traumatic brain injury in mice
Microglia-mediated neuroinflammation is one of the hallmark pathological features following traumatic brain injury (TBI) that contributes to aggravated brain damage and cognitive deficits. These pathologies require novel effective treatments to improve prognosis. Trametinib, a mitogen-activated prot...
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| Publicado no: | Am J Transl Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7653601/ https://ncbi.nlm.nih.gov/pubmed/33194035 |
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