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Rational Design of Evolutionarily Stable Microbial Kill Switches
The evolutionary stability of synthetic genetic circuits is key to both the understanding and application of genetic control elements. One useful but challenging situation is a switch between life and death depending on environment. Here are presented “essentializer” and “cryodeath” circuits, which...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812007/ https://ncbi.nlm.nih.gov/pubmed/29149596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.033 |
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