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Rational Design of Evolutionarily Stable Microbial Kill Switches

The evolutionary stability of synthetic genetic circuits is key to both the understanding and application of genetic control elements. One useful but challenging situation is a switch between life and death depending on environment. Here are presented “essentializer” and “cryodeath” circuits, which...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Stirling, Finn, Bitzan, Lisa, O’Keefe, Samuel, Redfield, Elizabeth, Oliver, John WK, Way, Jeffrey, Silver, Pamela A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812007/
https://ncbi.nlm.nih.gov/pubmed/29149596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.033
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