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The Importance of the Dissociation Rate in Ion Channel Blocking

Understanding the relationships between the rates and dynamics of current wave forms under voltage clamp conditions is essential for understanding phenomena such as state-dependence and use-dependence, which are fundamental for the action of drugs used as anti-epileptics, anti-arrhythmics, and anest...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Zeberg, Hugo, Nilsson, Johanna, Århem, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811512/
https://ncbi.nlm.nih.gov/pubmed/29479308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00033
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