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The Importance of the Dissociation Rate in Ion Channel Blocking

Understanding the relationships between the rates and dynamics of current wave forms under voltage clamp conditions is essential for understanding phenomena such as state-dependence and use-dependence, which are fundamental for the action of drugs used as anti-epileptics, anti-arrhythmics, and anest...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Zeberg, Hugo, Nilsson, Johanna, Århem, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811512/
https://ncbi.nlm.nih.gov/pubmed/29479308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00033
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