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Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4(+) Foxp3(−) T Cells into CD4(+) Foxp3(+) Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival
Regulatory T cells (Tregs) are critical players of immunological tolerance due to their ability to suppress effector T cell function thereby preventing transplant rejection and autoimmune diseases. During allograft transplantation, increases of both Treg expansion and generation, as well as their st...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811461/ https://ncbi.nlm.nih.gov/pubmed/29479348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00112 |
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