Vitamin C Fosters the In Vivo Differentiation of Peripheral CD4(+) Foxp3(−) T Cells into CD4(+) Foxp3(+) Regulatory T Cells but Impairs Their Ability to Prolong Skin Allograft Survival

Regulatory T cells (Tregs) are critical players of immunological tolerance due to their ability to suppress effector T cell function thereby preventing transplant rejection and autoimmune diseases. During allograft transplantation, increases of both Treg expansion and generation, as well as their st...

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Vydáno v:Front Immunol
Hlavní autoři: Oyarce, Karina, Campos-Mora, Mauricio, Gajardo-Carrasco, Tania, Pino-Lagos, Karina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811461/
https://ncbi.nlm.nih.gov/pubmed/29479348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00112
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