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Insights into the molecular motion of θ-defensins by NMR relaxation analysis

θ-Defensins are mammalian cyclic peptides that have antimicrobial activity and show potential as stable scaffolds for peptide-based drug design. The cyclic cystine ladder structural motif of θ-defensins has been characterized using NMR spectroscopy and is important for their structure and stability....

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Conibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A., Craik, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811197/
https://ncbi.nlm.nih.gov/pubmed/25375365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp507754c
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