Hypertonic Saline Primes Activation of the p53-p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines

Uncontrolled inflammatory responses underlie the etiology of acute lung injury and acute distress respiratory syndrome, the most common late complications in trauma, the leading cause of death under the age of 59. Treatment with HTS decreases lung injury in clinical trials, rat models of trauma and...

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Pubblicato in:J Proteome Res
Autori principali: Gamboni, Fabia, Anderson, Cameron, Mitra, Sanchayita, Reisz, Julie A., Nemkov, Travis, Dzieciatkowska, Monika, Jones, Kenneth L., Hansen, Kirk C., D’Alessandro, Angelo, Banerjee, Anirban
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811188/
https://ncbi.nlm.nih.gov/pubmed/27529569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00602
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