HYPERTONIC SALINE ATTENUATES TNF-α–INDUCED NF-κB ACTIVATION IN PULMONARY EPITHELIAL CELLS

Resuscitation with hypertonic saline (HTS) attenuates acute lung injury (ALI) and modulates postinjury hyperinflammation. TNF-α–stimulated pulmonary epithelium is a major contributor to hemorrhage-induced ALI. We hypothesized that HTS would inhibit TNF-α–induced nuclear factor (NF)–κB proinflammator...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Nydam, Trevor L., Moore, Ernest E., McIntyre, Robert C., Wright, Franklin L., Gamboni-Robertson, Fabia, Eckels, Phillip C., Banerjee, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799082/
https://ncbi.nlm.nih.gov/pubmed/18948845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31818ec47d
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