Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers

Hypertonic saline (HTS) has been used intravenously to reduce organ dysfunction following injury and as an inhaled therapy for cystic fibrosis lung disease. The role and mechanism of HTS inhibition was explored in the TNFα and IL-1β stimulation of pulmonary epithelial cells. Hyperosmolar (HOsm) medi...

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Udgivet i:PLoS One
Main Authors: Wright, Franklin L., Gamboni, Fabia, Moore, Ernest E., Nydam, Trevor L., Mitra, Sanchayita, Silliman, Christopher C., Banerjee, Anirban
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257597/
https://ncbi.nlm.nih.gov/pubmed/25479425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114129
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