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Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers

Hypertonic saline (HTS) has been used intravenously to reduce organ dysfunction following injury and as an inhaled therapy for cystic fibrosis lung disease. The role and mechanism of HTS inhibition was explored in the TNFα and IL-1β stimulation of pulmonary epithelial cells. Hyperosmolar (HOsm) medi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wright, Franklin L., Gamboni, Fabia, Moore, Ernest E., Nydam, Trevor L., Mitra, Sanchayita, Silliman, Christopher C., Banerjee, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257597/
https://ncbi.nlm.nih.gov/pubmed/25479425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114129
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