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Orphan G protein-coupled receptor GPRC5A modulates integrin β1-mediated epithelial cell adhesion
G-Protein Coupled Receptor (GPCR), Class C, Group 5, Member A (GPRC5A) has been implicated in several malignancies. The underlying mechanisms, however, remain poorly understood. Using a panel of human cell lines, we demonstrate that CRISPR/Cas9-mediated knockout and RNAi-mediated depletion of GPRC5A...
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Publicado no: | Cell Adh Migr |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5810789/ https://ncbi.nlm.nih.gov/pubmed/27715394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1245264 |
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