Family history and TOMM40 ‘523 interactive associations with memory in middle-aged and AD cohorts

INTRODUCTION: Family history (FH) of Alzheimer’s disease (AD) affects mitochondrial function, and may modulate effects of Translocase of Outer Mitochondrial Membrane–40kD (TOMM40) rs10524523 (‘523) poly-T length on memory decline. METHODS: For 912 non-Apolipoprotein ε4 (non-APOE4) middle-aged adults...

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Bibliografiske detaljer
Udgivet i:Alzheimers Dement
Main Authors: Willette, Auriel A., Webb, Joseph, Lutz, Michael W., Bendlin, Barbara B., Wennberg, Alexandra M, Oh, Jennifer M., Roses, Allen, Koscik, Rebecca L., Hermann, Bruce P., Dowling, N. Maritza, Asthana, Sanjay, Johnson, Sterling C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810361/
https://ncbi.nlm.nih.gov/pubmed/28549947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.03.009
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