Bu-Fei decoction and modified Bu-Fei decoction inhibit the growth of non-small cell lung cancer, possibly via inhibition of apurinic/apyrimidinic endonuclease 1

Human apurinic/apyrimidinic endonuclease 1 (APE1) is a ubiquitous multifunctional protein, which possesses DNA repair and redox activities. High levels of APE1 are associated with chemo- and radioresistance, and poor prognosis in various types of cancer, including non-small cell lung cancer (NSCLC)....

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Veröffentlicht in:Int J Mol Med
Hauptverfasser: Jiang, Shan-Tong, Han, Shu-Yan, Pang, Li-Na, Jiao, Yan-Na, He, Xi-Ran, Li, Ping-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810238/
https://ncbi.nlm.nih.gov/pubmed/29393411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3444
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