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Structure of the cold- and menthol-sensing ion channel TRPM8

Transient receptor potential melastatin (TRPM) cation channels are poly-modal sensors that are involved in a variety of physiological processes. Within the TRPM family, member 8 (TRPM8) is the primary cold- and menthol-sensor in humans. We determined the cryo-electron microscopy structure of the ful...

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Dades bibliogràfiques
Publicat a:Science
Autors principals: Yin, Ying, Wu, Mengyu, Zubcevic, Lejla, Borschel, William F., Lander, Gabriel C., Lee, Seok-Yong
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810135/
https://ncbi.nlm.nih.gov/pubmed/29217583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan4325
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