CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells

CXCR4 was the first receptor identified for CXCL12, but a second receptor, CXCR7, has also been described and its function in hematopoietic cells remains unknown. By inhibition of CXCR4 and/or CXCR7, we showed that CXCR7 participates in normal CD34(+) and U937 cell migration and prevents downregulat...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Melo, Rita de Cassia Carvalho, Ferro, Karla Priscila Viera, Duarte, Adriana da Silva Santos, Olalla Saad, Sara Teresinha
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810108/
https://ncbi.nlm.nih.gov/pubmed/29433559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0765-1
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