Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis

The crosstalk between hematopoietic stem/progenitor cells (HSC), both normal and leukemic, and their neighboring bone marrow (BM) microenvironment (niche) creates a reciprocal dependency, a master regulator of biological process, and chemotherapy resistance. In acute myeloid leukemia (AML), leukemic...

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Udgivet i:Front Cell Dev Biol
Main Authors: Roversi, Fernanda Marconi, Bueno, Maura Lima Pereira, Pericole, Fernando Viera, Saad, Sara Teresinha Olalla
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027121/
https://ncbi.nlm.nih.gov/pubmed/33842460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634044
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