Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1

Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. The processes and mechanisms that result in IAV mammalian adaptation are poorly understood. The viral nonstructural 1 (NS1) protein counteracts the interferon (IFN) response, a central...

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Bibliographic Details
Published in:	J Virol
Main Authors:	Chauché, C., Nogales, A., Zhu, H., Goldfarb, D., Ahmad Shanizza, A. I., Gu, Q., Parrish, C. R., Martínez-Sobrido, L., Marshall, J. F., Murcia, P. R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2018
Subjects:	Virus-Cell Interactions
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5809720/ https://ncbi.nlm.nih.gov/pubmed/29237841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01875-17
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Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1

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