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Nuclear Phosphatidylinositol-Phosphate Type I Kinase α-Coupled Star-PAP Polyadenylation Regulates Cell Invasion

Star-PAP, a nuclear phosphatidylinositol (PI) signal-regulated poly(A) polymerase (PAP), couples with type I PI phosphate kinase α (PIPKIα) and controls gene expression. We show that Star-PAP and PIPKIα together regulate 3′-end processing and expression of pre-mRNAs encoding key anti-invasive factor...

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Publicado en:Mol Cell Biol
Autores principales: A.P., Sudheesh, Laishram, Rakesh S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809686/
https://ncbi.nlm.nih.gov/pubmed/29203642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00457-17
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