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Phosphorylation regulates the Star-PAP-PIPKIα interaction and directs specificity toward mRNA targets

Star-PAP is a nuclear non-canonical poly(A) polymerase (PAP) that shows specificity toward mRNA targets. Star-PAP activity is stimulated by lipid messenger phosphatidyl inositol 4,5 bisphoshate (PI4,5P(2)) and is regulated by the associated Type I phosphatidylinositol-4-phosphate 5-kinase that synth...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Mohan, Nimmy, AP, Sudheesh, Francis, Nimmy, Anderson, Richard, Laishram, Rakesh S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538844/
https://ncbi.nlm.nih.gov/pubmed/26138484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv676
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