Gut Microbe–Mediated Suppression of Inflammation-Associated Colon Carcinogenesis by Luminal Histamine Production

Microbiome-mediated suppression of carcinogenesis may open new avenues for identification of therapeutic targets and prevention strategies in oncology. Histidine decarboxylase (HDC) deficiency has been shown to promote inflammation-associated colorectal cancer by accumulation of CD11b(+)Gr-1(+) imma...

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Vydáno v:Am J Pathol
Hlavní autoři: Gao, Chunxu, Ganesh, Bhanu Priya, Shi, Zhongcheng, Shah, Rajesh Rasik, Fultz, Robert, Major, Angela, Venable, Susan, Lugo, Monica, Hoch, Kathleen, Chen, Xiaowei, Haag, Anthony, Wang, Timothy C., Versalovic, James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809336/
https://ncbi.nlm.nih.gov/pubmed/28917668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.06.011
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