Age-dependent involvement of gut mast cells and histamine in post-stroke inflammation

BACKGROUND: Risk of stroke-related morbidity and mortality increases significantly with age. Aging is associated with chronic, low-grade inflammation, which is thought to contribute to the poorer outcomes after stroke seen in the elderly. Histamine (HA) is a major molecular mediator of inflammation,...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Blasco, Maria Pilar, Chauhan, Anjali, Honarpisheh, Pedram, Ahnstedt, Hilda, d’Aigle, John, Ganesan, Arunkumar, Ayyaswamy, Sriram, Blixt, Frank, Venable, Susan, Major, Angela, Durgan, David, Haag, Anthony, Kofler, Julia, Bryan, Robert, McCullough, Louise D., Ganesh, Bhanu Priya
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236952/
https://ncbi.nlm.nih.gov/pubmed/32429999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01833-1
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