Diacylglycerol kinase synthesized by commensal Lactobacillus reuteri diminishes Protein Kinase C phosphorylation and histamine-mediated signaling in the mammalian intestinal epithelium

Lactobacillus reuteri 6475 (Lr) of the human microbiome synthesizes histamine and can suppress inflammation via type 2 histamine receptor (H2R) activation in the mammalian intestine. Gut microbes such as Lr promote H2R signaling and may suppress H1R pro-inflammatory signaling pathways in parallel by...

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Pubblicato in:Mucosal Immunol
Autori principali: Ganesh, Bhanu Priya, Hall, Anne, Ayyaswamy, Sriram, Nelson, James Willard, Fultz, Robert, Major, Angela, Haag, Anthony, Esparza, Magdalena, Lugo, Monica, Venable, Susan, Whary, Mark, Fox, James G., Versalovic, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785580/
https://ncbi.nlm.nih.gov/pubmed/28745328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.58
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