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Simultaneous recognition of allogeneic MHC and cognate autoantigen by autoreactive T cells in transplant rejection

The autoimmune condition is a primary obstacle to inducing tolerance in type 1 diabetes patients receiving allogeneic pancreas transplants. It is unknown how autoreactive T cells that recognize self MHC molecules contribute to MHC-disparate allograft rejection. In this report, we show the presence a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Burrack, Adam L., Landry, Laurie G., Siebert, Janet, Coulombe, Marilyne, Gill, Ronald G., Nakayama, Maki
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809255/
https://ncbi.nlm.nih.gov/pubmed/29311365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700856
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