Prognostic Value of TERT Alterations and Mutational and Copy Number Alteration Burden in Urothelial Carcinoma

Point mutations in the TERT gene promoter occur at high frequency in multiple cancers, including urothelial carcinoma (UC). However, the relationship between TERT promoter mutations and UC patient outcomes is unclear owing to conflicting reports in the literature. In this study we examined the assoc...

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Publicado en:Eur Urol Focus
Main Authors: Isharwal, Sumit, Audenet, François, Drill, Esther, Pietzak, Eugene J., Iyer, Gopa, Ostrovnaya, Irina, Cha, Eugene, Donahue, Timothy, Arcila, Maria, Jayakumaran, Gowtham, Berger, Michael F., Rosenberg, Jonathan E., Bajorin, Dean F., Coleman, Jonathan, Dalbagni, Guido, Reuter, Victor E., Bochner, Bernard H., Solit, David B., Al-Ahmadie, Hikmat A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809230/
https://ncbi.nlm.nih.gov/pubmed/28802642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euf.2017.07.004
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