Autologous T cells expressing the oncogenic transcription factor KLF6-SV1 prevent apoptosis of chronic lymphocytic leukemia cells

Crosstalk between leukemic cells and the tumor microenvironment is of importance in chronic lymphocytic leukemia (CLL). T cells seem to sustain the survival of CLL cells by various mechanisms. The Krüppel-like family of transcription factors (KLFs) are identified as regulators of proliferation and c...

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Publicat a:PLoS One
Autors principals: Kokhaei, Parviz, Hojjat-Farsangi, Mohammad, Mozaffari, Fariba, Moshfegh, Ali, Pak, Fatemeh, Rashidy-Pour, Ali, Palma, Marzia, Hansson, Lotta, Österborg, Anders, Mellstedt, Håkan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809069/
https://ncbi.nlm.nih.gov/pubmed/29432497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192839
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