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T cells in chronic lymphocytic leukemia display dysregulated expression of immune checkpoints and activation markers
Chronic lymphocytic leukemia is characterized by impaired immune functions largely due to profound T-cell defects. T-cell functions also depend on co-signaling receptors, inhibitory or stimulatory, known as immune checkpoints, including cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) and progra...
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| Udgivet i: | Haematologica |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ferrata Storti Foundation
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5394965/ https://ncbi.nlm.nih.gov/pubmed/27927767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151100 |
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