Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers

In many different human disorders, the cellular glycome is altered. An interesting but poorly understood alteration occurs in the mucin-type O-glycome, in which there is aberrant expression of the truncated O-glycans Tn (GalNAcα1-Ser/Thr) and its sialylated version sialyl-Tn (STn) (Neu5Acα2,6GalNAcα...

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Bibliographic Details
Published in:Proteomics Clin Appl
Main Authors: Ju, Tongzhong, Wang, Yingchun, Aryal, Rajindra P., Lehoux, Sylvain D., Ding, Xiaokun, Kudelka, Matthew R., Cutler, Christopher, Zeng, Junwei, Wang, Jianmei, Sun, Xiaodong, Heimburg-Molinaro, Jamie, Smith, David F., Cummings, Richard D.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808880/
https://ncbi.nlm.nih.gov/pubmed/23857728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201300024
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