Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1

Leptin directly activates macrophages and lymphocytes, but the role of leptin in neutrophil activation and migration is still controversial. Here, we investigate the in vivo mechanisms of neutrophil migration induced by leptin. The intraperitoneal injection of leptin (1 mg/kg) induces a time- and co...

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Udgivet i:Front Immunol
Main Authors: Souza-Almeida, Glaucia, D’Avila, Heloisa, Almeida, Patricia E., Luna-Gomes, Tatiana, Liechocki, Sally, Walzog, Barbara, Hepper, Ingrid, Castro-Faria-Neto, Hugo Caire, Bozza, Patricia T., Bandeira-Melo, Christianne, Maya-Monteiro, Clarissa M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808117/
https://ncbi.nlm.nih.gov/pubmed/29467755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00111
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