Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1

Leptin directly activates macrophages and lymphocytes, but the role of leptin in neutrophil activation and migration is still controversial. Here, we investigate the in vivo mechanisms of neutrophil migration induced by leptin. The intraperitoneal injection of leptin (1 mg/kg) induces a time- and co...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Souza-Almeida, Glaucia, D’Avila, Heloisa, Almeida, Patricia E., Luna-Gomes, Tatiana, Liechocki, Sally, Walzog, Barbara, Hepper, Ingrid, Castro-Faria-Neto, Hugo Caire, Bozza, Patricia T., Bandeira-Melo, Christianne, Maya-Monteiro, Clarissa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808117/
https://ncbi.nlm.nih.gov/pubmed/29467755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00111
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