Leptin Elicits LTC(4) Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD(2) Receptors

Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by controlling activation of immunomodulatory cells, including eosinophils. While emerging as...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Amorim, Natália R. T., Luna-Gomes, Tatiana, Gama-Almeida, Marcos, Souza-Almeida, Glaucia, Canetti, Claudio, Diaz, Bruno L., Weller, Peter F., Torres Bozza, Patricia, Maya-Monteiro, Clarissa M., Bandeira-Melo, Christianne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160734/
https://ncbi.nlm.nih.gov/pubmed/30298073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02139
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