Allergic Challenge–Elicited Lipid Bodies Compartmentalize In Vivo Leukotriene C(4) Synthesis within Eosinophils

Eosinophils are an important source of leukotriene (LT)C(4), which can be synthesized within lipid bodies—cytoplasmic organelles where eicosanoid formation may take place. Allergy-driven lipid body formation and function have never been investigated. Here, we studied the in vivo induction and role o...

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Detalhes bibliográficos
Main Authors: Vieira-de-Abreu, Adriana, Assis, Edson F., Gomes, Gleice S., Castro-Faria-Neto, Hugo C., Weller, Peter F., Bandeira-Melo, Christianne, Bozza, Patrícia T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715315/
https://ncbi.nlm.nih.gov/pubmed/15947420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0145OC
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