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Intracrine Cysteinyl Leukotriene Receptor–mediated Signaling of Eosinophil Vesicular Transport–mediated Interleukin-4 Secretion

We investigated whether cysteinyl leukotrienes (cysLT) are intracrine signal transducers that regulate human eosinophil degranulation mechanisms. Interleukin (IL)-16, eotaxin, and RANTES stimulate vesicular transport–mediated release of preformed, granule-derived IL-4 and RANTES from eosinophils and...

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Detalhes bibliográficos
Main Authors: Bandeira-Melo, Christianne, Woods, Lesley J., Phoofolo, Mojabeng, Weller, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194050/
https://ncbi.nlm.nih.gov/pubmed/12235216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020516
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