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Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules

BACKGROUND: Cysteinyl leukotrienes are recognized to act via receptors (CysLTRs) expressed on cell surface plasma membranes. Agents that block CysLT(1)R, are therapeutics for allergic disorders. Eosinophils contain multiple preformed proteins stored within their intracellular granules. Cell-free eos...

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Main Authors: Neves, Josiane S., Radke, Amy L., Weller, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824614/
https://ncbi.nlm.nih.gov/pubmed/20159258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.11.029
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